مقایسه اثر کلسیم سولفات و فریک سولفات در کنترل خونریزی کبدی؛ مطالعه مدل حیوانی

Background: The control of parenchymal hemorrhage especially in liver parenchyma, despite surgical science progresses, is still one of the challenges surgeons face saving the patients&rsquo; lives and there is a research challenge between the researchers in this field to introduce a more effective method. This study aimed to compare the hemostatic effect of calcium sulfate and ferric sulfate on controlling the bleeding from liver parenchymal tissue. Methods: In this animal model study 60 male wistar rats were used. A length of two cm and a depth of half a cm incision was made on each mouse&rsquo;s liver and the hemostasis time was measured using calcium sulfate and ferric sulfate different concentrations (15%, 25%, and 50%). Finally, the obtained data were entered into SPSS software and analyzed using Kruskal-wallis test, Mann &ndash; Whitney, Kolmogorov &ndash; Smirnov and also Wilcoxon signed ranks test. Results: In all groups we had complete hemostasis. The hemostasis time of calcium sulfate concentration groups was significantly less than that of the ferric sulfate group (p<0.01). Conclusion: Calcium sulfate and ferric sulfate can control liver bleeding and both are effective hemostatic agents in controlling liver parenchymal tissue hemorrhage in an animal model.